WASHINGTON - Anyone who's had a hospital stay knows the beeping monitors, the pagers and phones, the hallway chatter, the roommate, even the squeaky laundry carts all make for a not-so-restful place to heal.
Hospitals need a prescription for quiet, and new research suggests it may not be easy to tamp down all the noise for a good night's sleep.
In fact, the wards with the sickest patients - the intensive care units - can be the loudest.
"It's just maddening," says Dr. Jeffrey Ellenbogen, sleep medicine chief at Massachusetts General Hospital. He pointed to one study that found the decibel level in ICUs reaches that of a shout about half the time.
Patient satisfaction surveys are packed with complaints that the clamor makes it hard to sleep.
Yet remarkably little is known about exactly how that affects patients' bodies - and which types of noises are the most disruptive to shut-eye. So Ellenbogen and researchers from Harvard and the Cambridge Health Alliance recorded different kinds of hubbub in a community hospital in Boston's suburbs to try to find out.
Since it wouldn't be appropriate to experiment on sick people by disrupting their sleep, 12 healthy volunteers were enlisted. They spent three nights in Mass General's sleep lab, slumbering as recorded hospital sounds blared from nearby speakers at increasing volumes.
Sure, a toilet flushing, voices in the hallway or the ice machine woke people once they were loud enough.
But electronic sounds were the most likely to arouse people from sleep - even at decibel levels not much above a whisper, the researchers reported Monday in the journal Annals of Internal Medicine.
What electronic sounds? Particularly troublesome was the beep-beep-beep from IV machines that signals someone needs more fluid or medicine, one of the most common machines in a hospital. They're just one of a variety of alarms.
Those alarms are meant to alert hospital workers, of course, but the finding raises a conundrum. So some hospitals are testing ways to make at least some monitors flash signals at the nurses' stations rather than sound loudly at the bedside.
The other surprises: The sleepers' heart rates temporarily jumped as much as 10 beats a minute as they were aroused, the researchers reported.
And they didn't remember most of the disruptions even though brain recordings clearly showed their sleep was interrupted, which suggests the problem is underestimated.
"My God, we delivered 100 sounds to this person and woke them up 40 times, and they're reporting to us just a couple" of awakenings, Ellenbogen said.
Regularly getting too little sleep plays a role in a number of health troubles, including high blood pressure, obesity, weakened immune system and, in particular, delirium.
Delirium is a dangerous state of confusion and agitation linked to sleep deprivation and broken sleep cycles, and is often experienced by hospitalized older people, Ellenbogen said.